not coincidentally, maine has a high rate of whooping cough cases � 21.1 per 100,000 people in 2015, compared to 10.3 per 100,000 nationwide. ., and bones, and it�s not clear how the drugs will affect them after long-term use. .-related side effects. its manufacturer, eli lilly, plans to submit a new drug application to the fda in the second half of 2018.